The proposed register would initially focussed on idiopathic scoliosis, but other scoliosis syndromes could be included in the future. The register would be developed in the British Isles, consisting of between 2,000 and 10,000 patients with scoliosis from various ethnic backgrounds. The main national centres of excellence in scoliosis are expected to contribute to the register, starting with an initial 6 month-pilot study involving two centres. The following data will be collected for each patient taking part on the register: - Saliva (for DNA extraction and analysis) - X- Rays - Family histor - Medical background All data will then be anonymised and stored in a reliable database that would be accessible to approved researchers investigating appropriate hypothesis. This register would contribute to the finding of the cause (s) of Adolescent Idiopathic Scoliosis and would also benefit all patients suffering form this condition.