Strangles is caused by the bacterium Streptococcus Equi and is the most commonly diagnosed infectious disease of horses worldwide. Clinial signs include fever, profuse nasal discharge and abcessed lymph nodes of the head and neck. The swelling of these lymph nodes may, in severe cases, restrict the airway, hence the name 'Strangles'. Scientists at the Animal Health Trust have discovered that S.equi has genetic characteristics typically found in Yersinia Pestis - the causive agent of human plague. Although S.equi does not present a risk to people, it could be said to represent the equine equivalent of human plague. Research: Currently , the scientists at the AHT are developing blood tests capable of identifying long-term carriers of Strangles. This will enable us to reduce disease spread. Safe and effective Strangles vaccines are also being designed which will benefit all individuals and groups with an interest in equine health and welfare. One vaccine product from our research was recently found to be safe on intramuscular administration to horses and we are now raising funds to continue the development of this exciting new Strangles vaccine. We plan to raise £250,000 to fund the vital research and help us end suffering of so many horses.