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This project will aid the development of new drugs to treat Alzheimer’s. It will examine how the tau protein, that ‘tangles’ up during the disease, can damage nerve cells. The project will use adult stem cells that will be turned into nerve cells, so the disease can be studied in the lab.
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Beneficiaries
Situation
Alzheimer’s and other dementias affect around 820,000 people in the UK today; this number is forecast to grow. It is a devastating disease that robs people of memories, personality and eventually their lives. At the moment there are no effective treatments for the disease. Alzheimer’s and other dementias have an economic impact to the UK of £23 billion per year, yet research into Alzheimer’s is drastically underfunded.
Solution
This project is one of 179 research projects that the Alzheimer’s Research Trust is currently supporting. In line with the charity’s vision, this project will move us towards a world free from dementia. This project will bring us closer to understanding the causes of Alzheimer’s and what damages nerve cells in the brain during the disease. This will in turn help the development of new drugs to treat Alzheimer’s.