The latest generation cutting edge equipment is needed in Bristol to determine the efficacy of novel drugs and the effect of cell based therapies towards regenerating the retina for research into the commonest causes of blindness.
It ran from 12:00 AM, 1 December 2010 to 12:00 AM, 1 December 2011
The commonest causes of blindness in the western world are due to abnormalities of the retinal vasculature. Firstly, diabetic retinopathy results from danage to retinal blood vessels and this occurs in many diabetics. Secondly: advanced age-related macular degeneration resulting in loss of vision in 26,000 patients per year in the UK; and finally, inflammatory eye diseases, which are a leading cause of blindness in the worked age group.
The equipment we are seeking support to purchase will enable researchers to: * characterise the evolution of retinal vascular pathology; * detect immune cells that track through the retinal circulation; * determine the true efficacy of the novel drugs that are developed in our laboratories to prevent blindness; * determine effect of cell based therapies toward regenerating the retiina.
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