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This study will look in detail at how cellular responses relate to clinical disease and aims to improve the management of eczema and other atopic diseases.
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Atopic eczema is the most common skin disease in the UK affecting up to 25% of the population. Eczema is especially prevalent in children, affecting at least 10% of infants. It has been shown by work here in Oxford that people with eczema react to harmless environmental allergens such as house dust mite. Central to this immune response are white blood cells called T-cells. This study will look in detail at how the cellular responses relate to clinical disease. The findings could be used to understand what makes disease progress, develop treatments and improve management of eczema and other atopic diseases. This year long project will cost £10,000, which covers the cost of the consumables.