This campaign has now closed
Restore was founded in 1991 to support research into burns and their treatment and to provide for innovative reconstructive surgery, particularly for patients undergoing therapy and surgery for breast cancer. We seek additional support for two Research Fellows, funded over 5 years at a total programme cost of £500,000. With that level of support we will be part of the increasing community of biomedical scientists who believe that we can solve the “scarring problem” an achievement, which, if realised, will bring enormous benefit to humanity.
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Restore's high standard of research been maintained and the results produced by our Research Fellows, both past and present, are making significant impact in the endeavour to eliminate the catastrophic effect of scarring on burns, disease and trauma victims. The three areas, which we can continue to make significant progress, are – 1. The further development of the proteomics programme to establish the correlation of the structures of the nine enzymes with their clinical function. 2. The elucidation of the process of blood vessel formation within the wound itself where we suggest there is prima facie evidence that stem cells are crucial in the making of new vessels and hence critical to the overall process of burns development and wound healing. 3. The further characterisation of the genes involved in early wound healing and an investigation of any biochemical relation with the enzymes identified in the proteomics programme